Grünenthal has promoted tramadol as an opioid with a lower risk of dependence than that of traditional opioids. Grünenthal offered a theory that, since the M1 metabolite is the principal agonist at μ-opioid receptors, the delayed agonist activity reduces abuse liability. The norepinephrine reuptake inhibitor effects may also play a role in reducing dependence.
More to this, the term ‘opioid’ has been devised to refer to synthetic morphine like compounds. Many of these substances offer the same narcotic and pain relieving properties of morphine but they are not addicting.
Unfortunately, tramadol is not one of those synthetic morphine like compounds. There are cases of tramadol dependence. The use of this medication can be addicting and the best way to avoid this is not to take tramadol frequently. There are other drug alternatives, just ask your doctor or pharmacist about them.
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